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Pharmacogenomics: Opportunities and Barriers to Implementation
Apr 26, 2021 | Episode 75 | 27 mins

Dr. Ronald Leopold discusses implementation of pharmacogenomic screening...

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The Impact of Pharmacogenomics on Precision Medicine
Apr 21, 2021 | Episode 74 | 30 mins
Why does a medication effectively “cure” one patient while having little to...
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Metagenomics in the time of Covid-19: Clinical Metagenomics
Apr 01, 2021 | Episode 72 | 26 mins
Robert Schlaberg and Lauge Farnaes from IdByDNA join us in a two-part inter...
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Metagenomics in the time of Covid-19: Emerging Pathogens
Apr 01, 2021 | Episode 73 | 20 mins
Robert Schlaberg and Lauge Farnaes from IdByDNA join us to talk about the e...
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Genomic surveillance and testing for SARS-CoV-2
Mar 16, 2021 | Episode 71 | 25 mins
Christopher Mason from Weill Cornell Medicine discusses his multifaceted ap...
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Exploring the Genomic Diversity of Africa
Mar 01, 2021 | Episode 70 | 32 mins
Although Africa is the continent with the highest amount of genetic diversi...
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Developmental Biology Meets Immunotherapy
Sep 03, 2020 | Episode 69 | 24 mins
Although most developmental genes are silenced in adult somatic cells, some...
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Genomics and the End of the Diagnostic Odyssey
May 13, 2020 | Episode 68 | 21 mins
Whole genome sequencing can help diagnose genetic diseases in days and hold...
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Standardization of Clinical Whole Genome Sequencing
May 11, 2020 | Episode 67 | 21 mins
Whole genome sequencing has the potential to supplant the traditional stepw...
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Rapid Genome Sequencing of Critically Ill Children
Apr 29, 2020 | Episode 65 | 24 mins
Genetic diseases are the leading cause of death among infants that are hosp...
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Integrating Genomics with Behavioral Sciences
Apr 22, 2020 | Episode 64 | 26 mins
Behavioral medicine holds the promise of helping scientists better understa...
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Growing the Invertebrate Tree of Life with Genomics
Apr 01, 2020 | Episode 63 | 19 mins
Invertebrates make up 95% of all animal species. They’ve been around for hu...
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DNA Structural Variants from Microscope to Sequencer
Mar 19, 2020 | Episode 62 | 23 mins
Structural variants are relatively large changes in DNA sequence across the...
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Finding Rare Diseases and Genome Sequencing
Mar 04, 2020 | Episode 61 | 24 mins
According to the California Healthcare Institute, up to 10% of the populati...
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Genomics of Diet and Precision Nutrition
Feb 19, 2020 | Episode 60 | 24 mins
According to the CDC, up to 40% of adults in the United States are obese. D...
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Drug Discovery through Gene Regulation
Feb 06, 2020 | Episode 59 | 24 mins
Targeted drug discovery has traditionally focused on inhibiting or modulati...
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2019 and the Year in Genomics
Jan 22, 2020 | Episode 58 | 26 mins
In 2019, NGS continued to enable scientists to make great strides in unders...
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Comprehensive Genomic Tumor Profiling
Dec 11, 2019 | Episode 57 | 20 mins
NGS-based genomics assays can help characterize the genetic profile of a tu...
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Genomic Tumor Profiling and Precision Oncology
Nov 20, 2019 | Episode 56 | 23 mins
Understanding the mutational profile of a tumor can help to guide therapeut...
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Genomics and Feeding a Hungry World
Nov 06, 2019 | Episode 55 | 23 mins
Agriculture has sustained and enhanced human life for thousands of years, b...
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If tumors could talk
Oct 23, 2019 | Episode 54 | 22 mins
Cancer is one of the leading causes of death around the world, and 38% peop...
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NGS and New Frontiers in Infectious Disease
Oct 09, 2019 | Episode 53 | 22 mins
Sepsis is a serious medical condition typically caused by a bloodstream inf...
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DNA Stories of Australia’s First Peoples
Sep 25, 2019 | Episode 52 | 23 mins
To ensure global scientific benefit from genomics, we need a better underst...
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NGS Improves In Vitro Fertilization
Sep 11, 2019 | Episode 51 | 23 mins
The average risk of miscarriage in a healthy woman is 10-25%, and risk incr...
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Genetic Screening and Inherited Disorders
Aug 29, 2019 | Episode 50 | 22 mins
Genetic carrier screening is used to identify recessive mutations linked to...
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Sequencing the Cancer Epigenome
Aug 14, 2019 | Episode 49 | 25 mins
The epigenome is the chemicals and proteins that bind DNA and regulate gene...
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Genomics and Tiger Conservation in Nepal
Jul 31, 2019 | Episode 48 | 26 mins
Tigers are apex predators in the wild and vital to maintaining biodiversity...
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Escape from Limbo Land
Jul 17, 2019 | Episode 47 | 21 mins
Parents of children who suffer from a rare disease can sometimes find it di...
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Unravelling the Mystery of Autoimmunity
Jul 08, 2019 | Episode 46 | 24 mins
The immune system is skilled at determining friend from foe. But, our immun...
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Single Cell Omics and Cellular Immunology
Jun 19, 2019 | Episode 45 | 28 mins
NGS-based single cell genomics techniques can characterize the genetic mate...
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Neglected Diseases and the Impact of NGS
Jun 05, 2019 | Episode 44 | 26 mins
Neglected tropical diseases primarily impact the world’s poor, and more tha...
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Rare Disease and the Diagnostic Odyssey
May 23, 2019 | Episode 43 | 25 mins
Rare diseases affect millions of people around the world. Dr. Matt Might is...
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Finding Bad Bugs with NGS
May 08, 2019 | Episode 42 | 31 mins
At the recent European Congress of Clinical Microbiology and Infectious Dis...
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Genetics of Breast Cancer
Apr 25, 2019 | Episode 41 | 23 mins
An average risk woman in the US has about a 1 in 8 chance of developing bre...
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Next Generation Science Education
Apr 08, 2019 | Episode 40 | 27 mins
Science, technology, engineering, and math (STEM) industries need creative ...
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Ancient DNA and Human History
Mar 20, 2019 | Episode 39 | 31 mins
Who am I, and where do I come from? We’re all interested in these fundament...
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The Magic of Stem Cells and Embryogenesis
Mar 06, 2019 | Episode 38 | 21 mins
We all start life as a single egg cell, but after fertilization we grow int...
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Immune Cells and Their Search for Energy
Feb 21, 2019 | Episode 37 | 30 mins
Metabolic changes in immune cells can alter immune system biology. So, unde...
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Environmental and Societal Impact of Microbes
Feb 06, 2019 | Episode 36 | 21 mins
Our biggest environmental challenges ultimately relate to microbes, so stud...
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Genomics 2018 Looking Back and Looking Ahead
Jan 23, 2019 | Episode 35 | 26 mins
2018 was an awesome year for genomics and genomics research. In this specia...
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Estonia is a Model for Precision Healthcare
Jan 09, 2019 | Episode 34 | 25 mins
Dr. Tõnu Esko is Deputy Director of Research at the Estonian Biobank of the...
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RNA Sequencing is a Cell Biology Tool
Dec 18, 2018 | Episode 33 | 27 mins
Dr. Joshua Weiner is Professor of Biology at the University of Iowa and Ass...
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Genome Editing and CRISPR-Cas9
Dec 11, 2018 | Episode 32 | 28 mins
The CRISPR-Cas9 genome editing system is enabling scientists to make specif...
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Noninvasive Prenatal Testing and NIPT
Nov 01, 2018 | Episode 31 | 38 mins
In noninvasive prenatal testing (NIPT), a maternal blood sample provides ma...
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Genomics of Long-Term Memory
Oct 18, 2018 | Episode 30 | 24 mins
Long-term memories can last from minutes to a lifetime, and they are associ...
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Genome Assembly and A Genomic Jigsaw Puzzle
Oct 03, 2018 | Episode 29 | 20 mins
Sequencing a human genome requires 300 billion bases of DNA sequence, all o...
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Genetics of Deafness and Hearing Loss
Sep 19, 2018 | Episode 28 | 21 mins
Hereditary deafness is a relatively common disorder that affects about 1 in...
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Genetics of Autism and Psychiatric Disorders
Sep 05, 2018 | Episode 27 | 22 mins
Autism is a complex psychiatric disorder that affects 1 in 59 children in t...
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Genomics and Preimplantation Genetic Screening
Aug 23, 2018 | Episode 26 | 23 mins
In vitro fertilization (IVF) is a reproductive technology used to overcome ...
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Large Scale Genetic Risk Profiling in Dementia
Aug 09, 2018 | Episode 25 | 25 mins
Neurodegenerative diseases are characterized by the death of brain tissues....
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Eczema and the Human Skin Microbiome
Jul 12, 2018 | Episode 24 | 19 mins
Atopic dermatitis (eczema) is a skin inflammation disorder that affects nea...
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Using Genetics to Predict Heart Attack Risk
Jun 27, 2018 | Episode 23 | 22 mins
Familial hypercholesterolemia is a genetic disorder leading to elevated cho...
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Out of Africa and Genetics of the African Diaspora
Jun 15, 2018 | Episode 22 | 20 mins
African populations migrated out of Africa between the 15th and 19th centur...
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Cancer Epigenomics and A Cacophony of Gene Expression
Jun 07, 2018 | Episode 21 | 19 mins
Cancer is the second leading cause of death globally. Cancer is driven by D...
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Rare Genes and Rare Diseases
May 23, 2018 | Episode 20 | 18 mins
Up to 30 million Americans and 30 million Europeans are currently living wi...
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NHGRI's 2020 Vision for Genomics
Apr 22, 2018 | Episode 19 | 31 mins
The National Human Genome Research Institute, or NHGRI, has launched a new ...
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Genetics of Children's Complex Diseases From GWAS to NGS
Apr 11, 2018 | Episode 18 | 20 mins
Complex diseases are associated with genetic, environmental, and lifestyle ...
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Genomics of Endosymbiosis and Cells Within Cells
Mar 29, 2018 | Episode 17 | 18 mins
Eukaryotic cells and their membrane bound organelles evolved from the uptak...
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Brain on Fire and Genomics of Neuroinflammation
Mar 14, 2018 | Episode 16 | 19 mins
Encephalitis is a brain inflammation that affects 4 million people worldwid...
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Human Gut Microbiome and Beneficial Bacteria
Feb 22, 2018 | Episode 15 | 18 mins
The human gut microbiome includes trillions of microbes that are important ...
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Single Cell Genomics and Cell Ontology
Feb 08, 2018 | Episode 14 | 19 mins
Cell ontology is the vocabulary for defining cell types, and it's important...
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The Human Genome and What We Are Missing
Jan 25, 2018 | Episode 13 | 17 mins
The human genome was completely sequenced in 2003 - or, was it? Robert Fult...
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Human Microbiome and Our Second Human Genome
Nov 27, 2017 | Episode 12 | 15 mins
We live in harmony with trillions of microbes in and on our bodies - the hu...
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Targeted NGS Empowers Genetic Testing
Nov 03, 2017 | Episode 11 | 16 mins
According to the US National Library of Medicine's Genetic Testing Registry...
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Childhood Cancer Risk and Genetics
Oct 20, 2017 | Episode 10 | 17 mins
According to the US National Cancer Institute, 15,000 children and adolesce...
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Genomics and Protecting Endangered Species
Oct 06, 2017 | Episode 9 | 13 mins
The critically endangered Saimaa ringed seal is found only in Lake Saimaa, ...
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Making Sense of Cancer Genomes
Sep 22, 2017 | Episode 8 | 16 mins
To enable precision medicine in cancer, health care providers need a solid ...
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RNA Sequencing in Diagnostics
Sep 08, 2017 | Episode 7 | 16 mins
Personalized medicine involves using a patient's genomic information to bet...
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Genomics and Immune Diseases
Aug 25, 2017 | Episode 6 | 16 mins
In the United States, autoimmune diseases affect 24 million people, resulti...
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Food Spoilage and Genomics
Aug 10, 2017 | Episode 5 | 14 mins
Food spoilage in global supply chains costs over 35 billion US dollars annu...
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Finnish Genetics Aid Disease Research
Jul 07, 2017 | Episode 4 | 13 mins
The country of Finland is the largest population isolate in Europe, with a ...
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The EMBL Genomics Core Facility
Jun 06, 2017 | Episode 3 | 14 mins
Next generation sequencing, or NGS, has helped to fuel amazing scientific d...
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Uncovering Enhancer Hijacking Events in Cancer
May 23, 2017 | Episode 2 | 16 mins
Genetic variation can impact our susceptibility to developing diseases, lik...
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Single-Cell Genomics and Mars
Mar 30, 2017 | Episode 1 | 16 mins
Microbes have been around for billions of years, and they continue to shape...
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